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XLO

Xilio Therapeutics, Inc. (NASDAQ)

Healthcare — Biotechnology

Xilio Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery and development of masked immuno-oncology therapies. The company's pipeline includes XTX501, a bispecific PD-1 / masked IL-2, for patients with metastatic non-small cell lung cancer; Efarindodekin alfa, an investigational, masked IL-12, that is in Phase 2 clinical trial for patients with advanced solid tumors; and Vilastobart, an investigational tumor-activated, Fc-enhanced, high affinity binding anti-CTLA-4 monoclonal antibody. The company was founded in 2016 and is headquartered in Waltham, Massachusetts.

None 1 analysts
$9.22
$-0.36 (-3.76%)
Target: $20.00 (116.9%)
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Price History

52-Week Range

Fundamentals

Market Cap$60.62M
P/E Ratio (TTM)-
Forward P/E-15.90
EPS (TTM)$-2.28
Dividend Yield-
Profit Margin-58.52%
Revenue Growth331.70%
ROE-75.20%
Debt/Equity9.15
Recommendation None
Analyst Target$20.00
Analysts1
Indexes NASDAQ

Technical Indicators

RSI (14)76.0
Beta-0.09
SMA 20-
SMA 40-
52-Week High$12.74
52-Week Low$6.47
50-Day Avg$8.33
200-Day Avg$9.15
Avg Volume44.2K
Volume129

Performance Analysis

NEUTRAL

XLO presents a mixed picture with both positive and negative indicators.

~ Trading at 44% of its 52-week range.
- RSI at 76.0 indicates overbought conditions — a pullback may be due.
+ Price is above both the 50-day and 200-day moving averages — strong uptrend.
+ Strong revenue growth of 331.7% year-over-year.
- Operating at a loss with -58.5% margin.
~ Wall Street consensus is "none" from 1 analysts.
+ Average analyst target of $20.00 implies 116.9% upside.

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Last updated: Jul 02, 2026 13:38 UTC

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