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SPRO

Spero Therapeutics, Inc. (NASDAQ)

Healthcare — Biotechnology

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts.

Hold 3.0 / 5 1 analysts
$2.19
$-0.03 (-1.22%)
Target: $4.00 (82.4%)
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Price History

52-Week Range

Fundamentals

Market Cap$126.98M
P/E Ratio (TTM)8.12
Forward P/E-1.98
EPS (TTM)$0.27
Dividend Yield-
Profit Margin24.90%
Revenue Growth-95.60%
ROE35.12%
Debt/Equity4.67
Recommendation Hold 3.0
Analyst Target$4.00
Analysts1
Indexes NASDAQ

Technical Indicators

RSI (14)35.7
Beta1.46
SMA 20-
SMA 40-
52-Week High$3.22
52-Week Low$1.80
50-Day Avg$2.59
200-Day Avg$2.41
Avg Volume$1.01M
Volume78.9K

Performance Analysis

NEUTRAL

SPRO presents a mixed picture with both positive and negative indicators.

~ Trading at 28% of its 52-week range.
~ RSI at 35.7 is in neutral territory.
- Price is below both the 50-day and 200-day moving averages — in a downtrend.
+ P/E of 8.1 suggests the stock may be undervalued.
- Revenue declined 95.6% year-over-year.
+ Healthy profit margin of 24.9%.
~ Wall Street consensus is "Hold" from 1 analysts.
+ Average analyst target of $4.00 implies 82.4% upside.

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Last updated: Jul 02, 2026 13:32 UTC

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