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SLN

Silence Therapeutics plc (NASDAQ)

Healthcare — Biotechnology

Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Divesiran (SLN124), which is in Phase 2 development for polycythemia vera, and SLN548 for complement-mediated renal diseases. It also develops Zerlasiran (SLN360) for cardiovascular disease associated with elevated lipoprotein(a); SLN312 for dyslipidemia; SLN365 for hypercholesterolemia; and SLN098 for obesity. The company was formerly known as SR Pharma plc and changed its name to Silence Therapeutics plc in May 2007. Silence Therapeutics plc was incorporated in 1994 and is headquartered in London, United Kingdom.

Buy 1.7 / 5 6 analysts
$11.83
+$0.98 (+9.03%)
Target: $29.17 (146.5%)
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Price History

52-Week Range

Fundamentals

Market Cap$508.95M
P/E Ratio (TTM)-
Forward P/E-27.63
EPS (TTM)$-1.62
Dividend Yield-
Profit Margin-
Revenue Growth197.20%
ROE-92.56%
Debt/Equity0.28
Recommendation Buy 1.7
Analyst Target$29.17
Analysts6
Indexes NASDAQ

Technical Indicators

RSI (14)83.3
Beta1.48
SMA 20-
SMA 40-
52-Week High$11.06
52-Week Low$4.19
50-Day Avg$7.28
200-Day Avg$6.27
Avg Volume387.9K
Volume841.9K

Performance Analysis

BULLISH

SLN shows predominantly bullish signals based on its fundamentals and technicals.

- Trading near its 52-week high ($11.06), which may indicate limited upside.
- RSI at 83.3 indicates overbought conditions — a pullback may be due.
+ Price is above both the 50-day and 200-day moving averages — strong uptrend.
+ Strong revenue growth of 197.2% year-over-year.
+ Wall Street consensus is "Buy" from 6 analysts.
+ Average analyst target of $29.17 implies 146.5% upside.

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Last updated: Jul 02, 2026 13:31 UTC

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