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OBIO

Orchestra BioMed Holdings, Inc. (NASDAQ)

Healthcare — Biotechnology

Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States. The company's flagship product candidates include Atrioventricular Interval Modulation, a bioelectronic therapy candidate designed to immediately, substantially, and persistently lower blood pressure; and Virtue Sirolimus AngioInfusion Balloon for the treatment of atherosclerotic artery disease. It also develops Cardiac Neuromodulation Therapy for heart failure, or potential treatment of clinical indications, such as urology or osteoarthritis; and CNT-HF, a bioelectronic product candidate that aims to reduce chronic sympathetic nervous system activity in heart failure. In addition, the company offers FreeHold devices and additional minimally invasive surgery enabling devices; and Pure-Vu system, a medical device to facilitate the cleansing of a poorly prepared gastrointestinal tract during colonoscopy and upper gastrointestinal endoscopy procedures. It has a collaboration agreement with Medtronic, Inc. for the development of AVIM therapy for the treatment of HTN in pacemaker-indicated patients; and a strategic collaboration with Terumo Corporation and Terumo Medical Corporation for the development and commercialization of Virtue SAB for the treatment of coronary and peripheral vascular disease. Orchestra BioMed Holdings, Inc. was founded in 2018 and is headquartered in New Hope, Pennsylvania.

None 6 analysts
$4.30
$-0.01 (-0.35%)
Target: $12.17 (182.9%)
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Price History

52-Week Range

Fundamentals

Market Cap$257.49M
P/E Ratio (TTM)-
Forward P/E-2.95
EPS (TTM)$-0.95
Dividend Yield-
Profit Margin-166.96%
Revenue Growth-87.30%
ROE-161.12%
Debt/Equity31.10
Recommendation None
Analyst Target$12.17
Analysts6
Indexes NASDAQ

Technical Indicators

RSI (14)56.9
Beta0.50
SMA 20-
SMA 40-
52-Week High$5.42
52-Week Low$2.20
50-Day Avg$4.03
200-Day Avg$4.03
Avg Volume316.2K
Volume266.8K

Performance Analysis

NEUTRAL

OBIO presents a mixed picture with both positive and negative indicators.

~ Trading at 65% of its 52-week range.
+ RSI at 56.9 shows positive momentum.
+ Price is above both the 50-day and 200-day moving averages — strong uptrend.
- Revenue declined 87.3% year-over-year.
- Operating at a loss with -167.0% margin.
~ Wall Street consensus is "none" from 6 analysts.
+ Average analyst target of $12.17 implies 182.9% upside.

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Last updated: Jul 02, 2026 13:24 UTC

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