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ENSC

Ensysce Biosciences, Inc. (NASDAQ)

Healthcare — Biotechnology

Ensysce Biosciences, Inc., a clinical-stage pharmaceutical company, develops prescription drugs for severe pain relief in opioid misuse, abuse, and overdose in the United States. It develops products using Trypsin Activated Abuse Protection (TAAP) platform, designed to release clinically effective drugs only when exposed to specific physiological conditions; and Multi-Pill Abuse Resistance (MPAR) platform, an over-dose protection opioid prodrug technology. The company's lead product candidate is PF614, a TAAP oxycodone prodrug candidate for the treatment of severe or chronic pain; and PF614-MPAR, a combination product of PF614 and nafamostat for overdose protection. It is also developing PF8001 and PF8026 are extended and immediate-release prodrugs of amphetamine for attention deficit hyperactivity disorder; and PF9001 to treat opioid use disorder. Ensysce Biosciences, Inc. was founded in 2003 and is based in La Jolla, California.

None 1 analysts
$0.30
+$0.01 (+4.14%)
Target: $16.45 (5347.0%)
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Price History

52-Week Range

Fundamentals

Market Cap$4.64M
P/E Ratio (TTM)-
Forward P/E-0.14
EPS (TTM)$-3.11
Dividend Yield-
Profit Margin-250.36%
Revenue Growth-27.20%
ROE-1149.11%
Debt/Equity-
Recommendation None
Analyst Target$16.45
Analysts1
Indexes NASDAQ

Technical Indicators

RSI (14)71.4
Beta0.82
SMA 20-
SMA 40-
52-Week High$2.75
52-Week Low$0.23
50-Day Avg$0.32
200-Day Avg$1.03
Avg Volume$2.27M
Volume298.1K

Performance Analysis

BEARISH

ENSC is flashing more cautionary signals — investors should monitor closely.

+ Trading near its 52-week low ($0.23), which could present a value opportunity.
- RSI at 71.4 indicates overbought conditions — a pullback may be due.
- Price is below both the 50-day and 200-day moving averages — in a downtrend.
- Revenue declined 27.2% year-over-year.
- Operating at a loss with -250.4% margin.
~ Wall Street consensus is "none" from 1 analysts.
+ Average analyst target of $16.45 implies 5347.0% upside.

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Last updated: Jul 02, 2026 13:08 UTC

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