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CSTL

Castle Biosciences, Inc. (NASDAQ)

Healthcare — Diagnostics & Research

Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), atopic dermatitis (AD), and uveal melanoma. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the likelihood of a positive sentinel lymph node and the risk of metastasis for patients with invasive cutaneous melanoma; TissueCypher, a risk stratification spatialomics test to predict future development of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, and low-grade dysplasia BE; AdvanceAD-Tx, a non-invasive GEP test which is designed to guide systemic treatment selection for patients aged 12 years and older with moderateto-severe AD; DecisionDx-SCC, a GEP test for cutaneous squamous cell carcinoma; and MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions. It also provides DecisionDx-UM, a risk stratification GEP test that predicts the risk of metastasis for patients with uveal melanoma. The company offers its products to dermatology and gastroenterology markets. The company was incorporated in 2007 and is headquartered in Friendswood, Texas.

Strong Buy 1.0 / 5 9 analysts
$24.71
+$0.86 (+3.61%)
Target: $43.56 (76.3%)
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Price History

52-Week Range

Fundamentals

Market Cap$749.45M
P/E Ratio (TTM)-
Forward P/E-26.48
EPS (TTM)$-0.42
Dividend Yield-
Profit Margin-3.78%
Revenue Growth-4.90%
ROE-2.85%
Debt/Equity7.96
Recommendation Strong Buy 1.0
Analyst Target$43.56
Analysts9
Indexes NASDAQ

Technical Indicators

RSI (14)79.1
Beta1.02
SMA 20-
SMA 40-
52-Week High$44.28
52-Week Low$14.59
50-Day Avg$21.74
200-Day Avg$28.70
Avg Volume401.4K
Volume311.3K

Performance Analysis

NEUTRAL

CSTL presents a mixed picture with both positive and negative indicators.

~ Trading at 34% of its 52-week range.
- RSI at 79.1 indicates overbought conditions — a pullback may be due.
- Revenue declined 4.9% year-over-year.
- Operating at a loss with -3.8% margin.
+ Wall Street consensus is "Strong Buy" from 9 analysts.
+ Average analyst target of $43.56 implies 76.3% upside.

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Last updated: Jul 02, 2026 13:04 UTC

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